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Apixaban Expert Views

last updatedTue, 25 Mar 2025
curated byTurnto community

What they liked

  • Experts appreciate Apixaban's role in reducing microclots.
  • Positive outcomes include improved blood flow and reduced symptoms.
  • Apixaban is part of effective triple therapy protocols.
  • Experts value its ability to target hyperactive platelets.

What they didn't like

  • Risk of serious bleeding, including brain and intestinal bleeds.
  • Concerns about safety in high-risk patients.
  • Some experts find triple therapy overly aggressive.
  • Limited data on long-term effects of Apixaban.

What are they unsure about

  • Experts question its effectiveness for all Long Covid patients.
  • Uncertainty about long-term safety and outcomes.
  • Lack of clarity on optimal dosage and duration.
  • Experts unsure about its role in autoimmune-related symptoms.

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3 expert views

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Expert view

Dr. Asad Khan discusses the use of anticoagulants, including Apixaban, in treating Long Covid. He highlights that removing clots and stabilizing the endothelium (the inner lining of blood vessels) can prevent recurrence of symptoms. He mentions that antibodies triggered by the spike protein may attack various parts of the body, and targeting these rogue antibodies might be necessary for some patients. Dr. Khan emphasizes the effectiveness of combining anticoagulants with apheresis, a blood filtration process, noting that this combination has reduced the number of treatment cycles needed. He also describes the three-drug regimen used, which includes aspirin, clopidogrel, and an anticoagulant like Apixaban, to address different aspects of clotting.

December 2021 • Episode 21: Dr Asad Khan - H.E.L.P. Apheresis

Expert view

Professor Jack Lambert, an infectious disease expert, discusses the use of anticoagulants like Apixaban for treating Long Covid. He acknowledges that while studies in the U.S. have shown some benefits, the risks are significant, including life-threatening complications like brain bleeds and intestinal bleeds. Lambert suggests safer alternatives, such as baby aspirin or natural supplements like natto kinase, which have anticoagulant effects and may work on the spike protein. He emphasizes the importance of avoiding risky treatments and focusing on safe options to improve patients' quality of life.

March 2023 • Episode 53: Prof. Jack Lambert - LDN protocol

Expert view

Saskia Mulder, a nurse living with Long Covid, shared her experience with Apixaban treatment during a visit to South Africa. She described how Dr. Jaco Laubscher explained the role of microclots and hyperactive platelets in Long Covid, which can block capillaries and cause damage to the endothelial layer inside blood vessels. Saskia's blood tests confirmed the presence of microclots and hyperactive platelets, leading to her prescription of a triple therapy that included Apixaban. She emphasized the importance of additional medications for managing side effects, such as menstrual cycle changes, when undergoing this therapy.

August 2022 • Long Covid Podcast

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